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A Study on Willis Ekbom Syndrome

Bhavya S.V., Priyadarshini .

Abstract


Willis Ekbom Syndrome (WES) is a neurological disorder. The individual with WES had poor quality of life since the client suffer from physical and psychological problems because of lack of sleep. WES is usually seen in the middle and later-aged population and females are most affected. The condition often goes unnoticed because of less severe symptoms in the initial period and correlated with other disorders. This article details its wide range of prevalence, risk factors, cause-related pathophysiology, criteria for diagnosing WES, symptoms, pharmacological and non-pharmacological management, and prognosis.


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References


National Institute of neurological disorders and stroke. Restless legs syndrome. Available from: https://www.ninds.nih.gov/health-information/disorders/restless-legs-syndrome.

Guo S, Huang J, Jiang H, Han C, Li J, Xu X et al. Restless legs syndrome: from pathophysiology to clinical diagnosis and management. Front Aging Neurosci. 2017 Jun 2;9:171. doi: 10.3389/fnagi.2017.00171.

Ishaq M, Riaz SU, Iqbal N, Siddiqui S, Moin A, Sajjad S et al. Prevalence of restless legs syndrome among medical students of Karachi: an experience from a developing country. Sleep Disord. 2020;2020:1–5. doi: 10.1155/2020/7302828.

Picchietti DL. Restless legs syndrome during pregnancy and lactation. Available from: https://www.uptodate.com/contents/restless-legs-syndrome-during-pregnancy-and-lactation/print.

Khan M, Mobeireek N, Al-Jahdali Y, Al-Dubyan N, Ahmed A, Al-Gamedi M, Et al. The prevalence of restless leg syndrome among pregnant Saudi women. Avicenna J Med. 2018;8(1):18–23. doi: 10.4103/ajm.AJM_123_17.

Almeneessie AS, Alyousefi N, Alzahrani M, Alsafi A, Alotaibi R, Olaish AH et al. Prevalence of restless legs syndrome among pregnant women: A case-control study. Ann Thorac Med. 2020;15(1):9–14. doi: 10.4103/atm.ATM_206_19.

Darvishi N, Daneshkhah A, Khaledi-Paveh B, Vaisi-Raygani A, Mohammadi M, Salari N et al. The prevalence of restless legs syndrome/Willis-Ekbom disease (RLS/WED) in the third trimester of pregnancy: a systematic review. BMC Neurol. 2020;20(1):132. doi: 10.1186/s12883–020–01709–0.

Berger K, Luedemann J, Trenkwalder C, John U, Kessler C. Sex and the risk of restless legs syndrome in the general population. Arch Intern Med. 2004;164(2):196–202. doi: 10.1001/archinte.164.2.196.

Maung SC, El Sara A, Chapman C, Cohen D, Cukor D. Sleep disorders and chronic kidney disease. World J Nephrol. 2016;5(3):224–32. doi: 10.5527/wjn.v5.i3.224.

Juárez Olguín H, Calderón Guzmán D, Hernández García E, Barragán Mejía G. The role of dopamine and its dysfunction as a consequence of oxidative stress. Oxid Med Cell Longev. 2016;2016:9730467. doi: 10.1155/2016/9730467.

Earley CJ, Jones BC, Ferré S. Brain-iron deficiency models of restless legs syndrome. Exp Neurol. 2022;356:114158. doi: 10.1016/j.expneurol.2022.114158.

Schwartz JR, Roth T. Neurophysiology of sleep and wakefulness: basic science and clinical implications. Curr Neuropharmacol. 2008;6(4):367–78. doi: 10.2174/157015908787386050.

Beh SC, Greenberg BM, Frohman T, Frohman EM. Transverse myelitis. Neurol Clin. 2013;31(1):79–138. doi: 10.1016/j.ncl.2012.09.008.

Joseph V, Nagalli S. Periodic limb movement disorder. StatPearls [Internet]. Updated 2022 Nov 27:2022 Jan-.

Nagandla K, De S. Restless legs syndrome: pathophysiology and modern management. Postgrad Med J. 2013;89(1053):402–10. doi: 10.1136/postgradmedj-2012–131634.

Maung SC, El Sara A, Chapman C, Cohen D, Cukor D. Sleep disorders and chronic kidney disease. World J Nephrol. 2016;5(3):224–32. doi: 10.5527/wjn.v5.i3.224.

Cleveland Clinic. Restless legs syndrome. Available from: https://my.clevelandclinic.org/health/diseases/9497-restless-legs-syndrome.

Picchietti DL, England SJ, Walters AS, Willis K, Verrico T. Periodic limb movement disorder and restless legs syndrome in children with attention-deficit hyperactivity disorder. J Child Neurol. 1998;13(12):588–94. doi: 10.1177/088307389801301202.

International Restless Legs Syndrome Study Group. IRLSSG Diagnostic Criteria for RLS; 2012. Available from: http://www.irlssg.org.

Lone Star Neurology. Take action in the fight against restless legs syndrome. Available from: https://lonestarneurology.net/restless-legs-syndrome/.

Webmed. Treatments for restless legs syndrome. Available from: https://www.webmd.com/brain/restless-legs-syndrome/restless-leg-syndrome-treatment.




DOI: https://doi.org/10.37628/ijin.v9i1.2331

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