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A Review on Topical Drug Delivery System: Proniosomal Powder of Flurbiprofen

ABHISHEK KUAMAR, Shubham Tripathi, Arpita Singh, Mayank Tiwari, Sonali Singh, Shubham Tiwari

Abstract


Proniosomal gel or solution of flurbiprofen was developed based on span 20, span 40, span 60, and span 80 without and with cholesterol but in the formulation of proteasomal gel or proteasomal powder, the primary surfactant plays an important role which is brij 35, and we add these surfactants in these formulations. Non-ionic surfactant vesicle noisome) formed immediately upon hydrating proniosomal; formulae. With the hope of mitigating the negative impact of oral administration, this study proposes to develop a gun-based proteasomal powder drug delivery system for flurbiprofen. Traditional chemotherapy for intracellular infection no longer works because of poor medication penetration into cells. One solution is to use a vesicular medication delivery system. The powdered form of a niosome is often clear, translucent, or white, which makes it easy to store and carry. Since there wasn't enough room in the solvent solution for everything, the proteasome developed as a complex combination of several liquid crystal phases. By encapsulating flurbiprofen in different formulations or proteasomal powder consisting of sorbital fatty acid generated using the slurry technique, researchers were able to examine the proteasome's potential as a transdermal drug delivery mechanism

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