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Isolation of Microbes from Valley of Flower (VOF) India and Screening of Actinomycetes for their Antibiotic Potential
Abstract
Microbial diversity depends on various factors. The habitat, niche and climatic conditions play a crucial role in species richness and uniqueness. In the search for new antimicrobial compound valley of flower (VOF) would be a hot spot because of its geographical location. It is one of the eighth world’s heritages and has no such reported studies. We have analysed 62 soil samples from different locations ranging the latitude 30°41′–30°48′ N and longitude 79°33′–79°46′ E to latitude 30°68′–30°8′ N and longitude 79°55′–79°76′ E. A total of 334 types of microbial communities with 54% actinomycetes, 24% fungi and 22% bacteria were observed. 17% of the isolated Actinomycetes were having antimicrobial property against one or more than one kind of pathogens tested. Out of 22 identified, 4 (Streptomyces diastaticus subsp. ardesiacus NRRL B-1773(T), Streptomyces badius, Stenotrophomonas pavanii, and Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111(T)) are novel not known to produce antibiotics. The discovery of new antibiotics is even more urgent and desired in the current COVID-19 pandemic. There is high potential of VOF niche for a novel antibiotic.
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References
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